2024 ISS National Lab Annual Report Highlights Momentum in Space-Based R&D

KENNEDY SPACE CENTER (FL), January 28, 2025 – The International Space Station (ISSInternational Space Station) National Laboratory highlighted the rapid growth of space-based R&D in its annual report, released today by the Center for the Advancement of Science in Space® (CASIS®). Over the past fiscal year, the ISS National Lab sponsored more than 100 payloads delivered to the orbiting laboratory—the second-highest annual total to date. Also during this fiscal year, nearly three-quarters of newly-selected projects sponsored for flight were from first-time space users, highlighting the success of the ISS National Lab in engaging new research communities.

Since 2011, CASIS has managed the ISS National Lab under a Cooperative AgreementA cooperative agreement is Federal assistance that establishes a relationship between the U.S. Government and a recipient in which the principal purpose of the relationship is to accomplish a public purpose of support or stimulation.  Since 2011, the Center for the Advancement of Science in Space™ (CASIS™) has managed the National Laboratory® through a Cooperative Agreement with NASA. with NASANational Aeronautics and Space Administration, enabling access to the space station to benefit humanity and stimulate a thriving low Earth orbit(Abbreviation: LEO) The orbit around the Earth that extends up to an altitude of 2,000 km (1,200 miles) from Earth’s surface. The International Space Station’s orbit is in LEO, at an altitude of approximately 250 miles. (LEO) economy. This partnership with NASA supports the ISS National Lab’s mission to advance space-based R&D, foster a sustainable market economy in space, and pave the way for future commercial LEO destinations (CLDs). The ISS National Lab’s annual report for fiscal year 2024 (October 1, 2023-September 30, 2024) showcases the progress toward these goals.

Below are a few notable accomplishments from FY24:

• Of the 103 ISS National Lab-sponsored payloads launched to the space station, 80 percent were from commercial entities, indicating a continued strong interest from private industry to conduct R&D in space.
• Nearly 75 percent of newly selected projects in FY24 were from new-to-space users, highlighting the success of ISS National Lab solicitations in attracting new research communities. Of the 31 selected projects, more than half were through ISS National Lab Research Announcements (NLRAs) in the strategic focus areas of technology development, in-space production applications(Abbreviation: InSPA) InSPA is an applied research and development program sponsored by NASA and the ISS National Lab aimed at demonstrating space-based manufacturing and production activities by using the unique space environment to develop, test, or mature products and processes that could have an economic impact. (tissue engineering and biomanufacturing), and workforce development.
• More than 50 peer-reviewed articles related to ISS National Lab research—the most identified in a single fiscal year—were published in FY24, bringing the all-time total to nearly 450. Two-thirds of these papers were related to projects funded by the U.S. National Science Foundation (NSF) and the National Institutes of Health (NIH).
• An NIH-funded project resulted in a patent filed for a muscle tissue chipA tissue chip, or organ-on-a-chip or microphysiological system, is a small engineered device containing human cells and growth media to model the structure and function of human tissues and/or organs. Using tissue chips in microgravity, researchers can study the mechanisms behind disease and test new treatments for patients on Earth. The National Institutes of Health (NIH) has a multiyear partnership with the ISS National Laboratory® to fund tissue chip research on the space station. system, and an ISS National Lab-sponsored educational project led to a new product: a space station model kit for educators and students.
• Nearly $25 million in external, non-NASA funding was committed in support of ISS National Lab-sponsored projects, with almost half from academic and nonprofit institutions—underscoring the value they find in space-based R&D.
• The ISS National Lab allocated significant funding to the inaugural Igniting Innovation solicitation, in partnership with NASA’s Biological and Physical Sciences Division. The solicitation offered $7 million to five selected multiflight projects to advance critical cancer research. Most were from academic and nonprofit institutions that matched funding 1:1.
• Despite challenging market conditions, startups secured nearly $147 million in funding after the flight of ISS National Lab-sponsored projects, bringing the cumulative total to $2.2 billion.
• Subscribership nearly doubled for Upward, official magazine of ISS National Lab, while the Space Station SpotlightThe monthly newsletter from the ISS National Laboratory® providing information on the latest space station research, updates from ISS National Lab partners, exciting results from space-based research, and important funding opportunities. newsletter, which launched in FY23, added 1,100 new subscribers in FY24. Both boosted awareness of ISS National Lab activities and R&D results, while a redesigned website doubled page views by creating clearer engagement pathways.
• This year, the ISS National Lab prioritized workforce development and STEM career readiness, launching activities to equip students with essential skills. A new corporate donor pledged funding to support these education initiatives over the next three years.

“I am incredibly proud of what we achieved this year,” said Ramon Lugo, principal investigator and chief executive officer of CASIS. “As we continue to work hand in hand with NASA, our strong partnership has allowed us to push the limits of what we can accomplish.”

The FY24 Annual Report is now available online. To read about additional ISS National Lab-sponsored research that has launched to the space station, visit our website.

Download a high-resolution image for this release: ISS National Lab Annual Report

Media Contact:
Patrick O’Neill
904-806-0035
PONeill@ISSNationalLab.org

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About the International Space Station (ISS) National Laboratory: The International Space Station (ISS) is a one-of-a-kind laboratory that enables research and technology development not possible on Earth. As a public service enterprise, the ISS National Laboratory® allows researchers to leverage this multiuser facility to improve quality of life on Earth, mature space-based business models, advance science literacy in the future workforce, and expand a sustainable and scalable market in low Earth orbit. Through this orbiting national laboratory, research resources on the ISS are available to support non-NASA science, technology, and education initiatives from U.S. government agencies, academic institutions, and the private sector. The Center for the Advancement of Science in Space™ (CASIS™(Abbreviation: CASIS™) The nonprofit organization that manages the ISS National Lab, which receives at least 50 percent of the U.S. research allocation on the International Space Station to facilitate research that benefits humanity (NASA manages the other 50% and focuses on research for space exploration purposes).) manages the ISS National Lab, under Cooperative Agreement with NASA, facilitating access to its permanent microgravityThe condition of perceived weightlessness created when an object is in free fall, for example when an object is in orbital motion. Microgravity alters many observable phenomena within the physical and life sciences, allowing scientists to study things in ways not possible on Earth. The International Space Station provides access to a persistent microgravity environment. research environment, a powerful vantage point in low Earth orbit, and the extreme and varied conditions of space. To learn more about the ISS National Lab, visit our website.

As a 501(c)(3) nonprofit organization, CASIS accepts corporate and individual donations to help advance science in space for the benefit of humanity. For more information, visit our donations page.