NLRA 2024-1

National Lab Research Announcement

In-Space Production Applications: Tissue Engineering and Biomanufacturing

The purpose of this ISS National Lab Research Announcement (NLRA) is to solicit proposals for applied research and development seeking to demonstrate space-based biomanufacturing activities in microgravity. Flight projects selected via this research announcement may be awarded funding to enable support for development and mission integration and operations for projects that will be implemented on the ISS.

NLRA / NSF Solicitation #:
NLRA 2024-1

NLRA Open Period: Cycle 1:
10/4/2023 – 3/11/2024

Strategic Focus:
In-Space Manufacturing

Research Area:
Tissue Engineering

Watch the webinar to learn about this opportunity

iss065e085491 (June 3, 2021) NASA astronaut and Expedition 65 Flight Engineer Megan McArthur loads protein crystallography plates with protein solutions for the Real time Protein Crystal Growth experiment. The biotechnology study demonstrates new methods for producing high quality protein crystals in microgravity. Results may help identify new targets and develop better drugs to treat a variety of diseases on Earth and advance the commercialization of low Earth orbit.

NASA astronaut and Expedition 65 Flight Engineer Megan McArthur loads protein crystallography plates for the Real-time Protein Crystal Growth experiment.

Media Credit: NASA

CASIS, in coordination with NASA, has identified multiple ISS National Lab lines of business that support strategic priorities and programmatic focus areas aimed at bringing value to our nation and enabling a robust and scalable market in low Earth orbit. For the in-space production line of business, research concepts are desired for which space-based testing can uniquely enable technical solutions to known science and engineering challenges and the creation of new products and business opportunities.  The objective is to use the unique ISS environment to develop, test or mature products and processes that have a demonstrated potential to produce near-term, positive direct or indirect economic impact

Steps to Applying for This Research Opportunity

This research announcement will follow a two-step proposal submission process. Before being invited to submit a full proposal, all interested investigators must first complete and submit for review a Step 1: Concept Summary.

** Please verify that none of the information submitted is subject to the export control laws of the United States, such as the EAR or the ITAR; if any information is subject to such laws, please mark all pages containing such information and identify the appropriate export control jurisdiction and classification. **

Step 1.1: Download Instructions

Step 1.2: Concept summaries must be submitted electronically using the concept summary submission portal. To access the portal, press the “Click to Submit” button below.

Step 2.1: CASIS will notify all offerors of the review results of their Step 1: Concept Summary.

Step 2.1: If you were invited to submit a Step 2: Full Proposal, upload your submission by pressing the “Click to Submit” button below. Please convert your document to a PDF prior to uploading. Offerors should ensure they are using a current version of Adobe Acrobat to create their PDF and that uploaded documents do not include Flash content.

Thank you for your interest in conducting research leveraging the ISS National Lab! For questions regarding this research announcement, please contact info@ISSNationalLab.org and reference NLRA2024-1 in the subject line.