Next Mission to the Space Station Features Nanomaterials to Treat Osteoarthritis, New Materials for Lifelike Robotics, a Holographic Microscope, and More

KENNEDY SPACE CENTER (FL), April 18, 2025 – A project to manufacture nanomaterials that could provide new treatments for osteoarthritis and cancer joins a trio of investigations funded by the U.S. National Science Foundation (NSF) and more on SpaceX’s 32nd Commercial Resupply Services (CRS) mission for NASANational Aeronautics and Space Administration to the International Space Station (ISSInternational Space Station). These investigations, sponsored by the ISS National Laboratory®, aim to benefit humanity and foster a robust economy in low Earth orbit(Abbreviation: LEO) The orbit around the Earth that extends up to an altitude of 2,000 km (1,200 miles) from Earth’s surface. The International Space Station’s orbit is in LEO, at an altitude of approximately 250 miles. (LEO).

This mission is scheduled to launch no earlier than April 21, 2025, at 4:15 a.m. EDT, from Launch Complex 39A at NASA’s Kennedy Space Center in Florida. Below are highlights of ISS National Lab-sponsored investigations on this mission.

• Researchers from the University of Connecticut and Eascra Biotech, with support from Axiom Space, will build on previous research to improve the production of innovative nanomaterials in space to treat osteoarthritis and cancer on Earth. Janus base nanomaterials (JBNs) are composed of synthetic molecules that self-assemble into structures resembling human DNA. The injectable nanomaterials could help regenerate cartilage in the joints of osteoarthritis patients and could be used to carry cancer drugs into hard-to-penetrate solid tumors. The team’s groundbreaking research is featured in the most recent issue of Upward, the official magazine of the ISS National Lab.
• Three investigations funded by NSF seek to advance fundamental science with valuable applications. These projects continue a strong, multi-year collaboration between NSF and the ISS National Lab:
  • An investigation from Rensselaer Polytechnic Institute, supported by Tec-Masters, will use microgravityThe condition of perceived weightlessness created when an object is in free fall, for example when an object is in orbital motion. Microgravity alters many observable phenomena within the physical and life sciences, allowing scientists to study things in ways not possible on Earth. The International Space Station provides access to a persistent microgravity environment. to study fluid flow in protein solutions. The goal is to better understand why protein clumping occurs during the manufacturing of protein-based drugs, which affects their quality. In space, liquid forms into a floating self-contained sphere, allowing the study of complex protein motion without the walls of a container altering protein behavior. This project, which is a continuation of prior research, could help find a way to avoid or reverse protein clumping, which would address a significant challenge in the pharmaceutical industry.
  • A project from the University of Alabama at Birmingham, supported by Leidos, will study the formation and microstructure of ceramic-nanomaterial composites in microgravity to produce novel materials that are lightweight, electrically conductive, and stable in high-temperature environments. The materials can be made into almost any shape or size, making them valuable for many industrial applications such as energy storage, electric systems, and nanodevices.
  • Researchers from the University of California, Santa Barbara will conduct an investigation, supported by Redwire Space Technologies, to better understand active liquid-liquid phase separation (LLPS)—a phenomenon that occurs when two liquids that do not mix (such as oil and water) separate. Active LLPS could be used to create soft active materials with lifelike properties that can move and change shape on their own or sense and repair themselves. These materials could be used to make more lifelike robotics.
• Portland State University, in collaboration with NASA’s Jet Propulsion Laboratory in Southern California and Teledyne Brown Engineering, Inc., will test an advanced microscope system that uses holographic technology to deliver detailed 3D views of cellular life. The Extant Life Volumetric Imaging System (ELVIS) will allow scientists to study the adaptability and resilience of life under extreme conditions, which could enhance the search for life beyond Earth.
• An experiment from Sophie’s BioNutrients, supported by BioServe Space Technologies, aims to develop plant-based, protein-rich alternatives to meat and seafood using microalgae. The investigation will examine how microgravity affects protein yields in microalgae that require nutrition from organic compounds to grow. Results could provide insights into the fundamental mechanisms of microalgae cell growth, metabolism, and protein production. In addition to serving as a food source on long-duration spaceflight missions, the microalgae could also be used in life support systems and to provide oils for fuel production.

For more information on ISS National Lab-sponsored investigations on this mission, visit our launch page. To learn more about the research and technology development sponsored by the ISS National Lab, including how to propose concepts for future space-based research, visit our website.

Download a high-resolution image for this release: NASA’s SpaceX CRS 31 in November 2024

Media Contact:
Patrick O’Neill
904-806-0035
PONeill@ISSNationalLab.org

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About the International Space Station (ISS) National Laboratory: The International Space Station (ISS) is a one-of-a-kind laboratory that enables research and technology development not possible on Earth. As a public service enterprise, the ISS National Laboratory® allows researchers to leverage this multiuser facility to improve quality of life on Earth, mature space-based business models, advance science literacy in the future workforce, and expand a sustainable and scalable market in low Earth orbit. Through this orbiting national laboratory, research resources on the ISS are available to support non-NASA science, technology, and education initiatives from U.S. government agencies, academic institutions, and the private sector. The Center for the Advancement of Science in Space® (CASIS®) manages the ISS National Lab, under Cooperative AgreementA cooperative agreement is Federal assistance that establishes a relationship between the U.S. Government and a recipient in which the principal purpose of the relationship is to accomplish a public purpose of support or stimulation.  Since 2011, the Center for the Advancement of Science in Space™ (CASIS™) has managed the National Laboratory® through a Cooperative Agreement with NASA. with NASA, facilitating access to its permanent microgravity research environment, a powerful vantage point in low Earth orbit, and the extreme and varied conditions of space. To learn more about the ISS National Lab, visit our website.

As a 501(c)(3) nonprofit organization, CASIS(Abbreviation: CASIS™) The nonprofit organization that manages the ISS National Lab, which receives at least 50 percent of the U.S. research allocation on the International Space Station to facilitate research that benefits humanity (NASA manages the other 50% and focuses on research for space exploration purposes). accepts corporate and individual donations to help advance science in space for the benefit of humanity. For more information, visit our donations page.