Looking to Microgravity Crystallization for a Cancer Cure
KENNEDY SPACE CENTER (FL), April 27, 2023 – In their quest to discover a cure for cancer, a team of researchers at Frederick National Laboratory for Cancer Research turned to the International Space Station (ISSInternational Space Station) National Laboratory to do something they couldn’t do on Earth—remove gravity.
For more than 20 years, scientists have used protein crystallization to try to get the detailed structure of a protein linked to several of the deadliest cancers, but all attempts have been unsuccessful. That’s because gravity-driven forces can make it difficult to grow high-quality crystals on Earth. However, in microgravityThe condition of perceived weightlessness created when an object is in free fall, for example when an object is in orbital motion. Microgravity alters many observable phenomena within the physical and life sciences, allowing scientists to study things in ways not possible on Earth. The International Space Station provides access to a persistent microgravity environment., where these forces are removed, crystals often grow larger and more well-ordered than crystals grown in ground-based labs. This makes the ISS an ideal environment for protein crystallization.
The newest issue of Upward, the official magazine of the ISS National Lab, highlights results from this exciting research. Upward is dedicated to communicating results of ISS experiments that demonstrate the value of space-based research and development. Read the article “Space Crystals and the Search for a Cancer Cure” to see how scientists are using microgravity to improve protein crystallization that could help patients on Earth.
Media Contact:
Patrick O’Neill
904-806-0035
PONeill@ISSNationalLab.org
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About the International Space Station (ISS) U.S. National Laboratory: The International Space Station (ISS) is a one-of-a-kind laboratory that enables research and technology development not possible on Earth. As a public service enterprise, the ISS National Lab allows researchers to leverage this multiuser facility to improve life on Earth, mature space-based business models, advance science literacy in the future workforce, and expand a sustainable and scalable market in low Earth orbit(Abbreviation: LEO) The orbit around the Earth that extends up to an altitude of 2,000 km (1,200 miles) from Earth’s surface. The International Space Station’s orbit is in LEO, at an altitude of approximately 250 miles.. Through this orbiting national laboratory, research resources on the ISS are available to support non-NASA science, technology and education initiatives from U.S. government agencies, academic institutions, and the private sector. The Center for the Advancement of Science in Space, Inc. (CASIS(Abbreviation: CASIS™) The nonprofit organization that manages the ISS National Lab, which receives at least 50 percent of the U.S. research allocation on the International Space Station to facilitate research that benefits humanity (NASA manages the other 50% and focuses on research for space exploration purposes).) manages the ISS National Lab, under Cooperative AgreementA cooperative agreement is Federal assistance that establishes a relationship between the U.S. Government and a recipient in which the principal purpose of the relationship is to accomplish a public purpose of support or stimulation. Since 2011, the Center for the Advancement of Science in Space™ (CASIS™) has managed the National Laboratory® through a Cooperative Agreement with NASA. with NASANational Aeronautics and Space Administration, facilitating access to its permanent microgravity research environment, a powerful vantage point in low Earth orbit, and the extreme and varied conditions of space. To learn more about the ISS National Lab, visit issnationallab.org.
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