NASA astronaut Kate Rubins works inside the Life Sciences Glovebox

Open Period: 12/1/2022-3/6/2023

NSF/CASIS 2023 Collaboration on Tissue Engineering and Mechanobiology on the ISS to Benefit...

The purpose of this solicitation is to attract proposals that make use of the ISS National Lab for flight research projects in the field of biomedical engineering.

Past Opportunity  
ss068e006386 (Oct. 1, 2022) NASA astronaut and Expedition 68 Flight Engineer Frank Rubio has fun with fluid physics as he observes the behavior of a free flying water bubble inside the International Space Stations Kibo laboratory module.

Open Period: 12/1/2022-3/6/2023

NSF/CASIS 2023 Collaboration on Transport Phenomena Research on the ISS to Benefit Life on...

The purpose of this solicitation is to attract proposals to leverage the ISS National Lab for research related to the NSF Transport Phenomena Cluster and Nanoscale Interaction programs.

Past Opportunity  
ESA astronaut and Expedition 65 Flight Engineer Thomas Pesquet works on the Cardinal Muscle investigation in the Life Sciences Glovebox aboard the ISS.

Open Period: 10/3/2023 – 2/28/2023

NLRA 2023-2: In-Space Production Applications: Tissue Engineering and Biomanufacturing

The purpose of this NLRA is to solicit proposals for applied R&D seeking to demonstrate space-based biomanufacturing activities in microgravity.

Past Opportunity  
NASA astronaut Thomas Marshburn configures the Combustion Integrated Rack's combustion chamber for the Solid Fuel Ignition and Extinction study to investigate material flammability and ways to improve fire safety in space.

Open Period: 9/15/2022-3/29/2023

NLRA 2023-1: Technology Advancement and Applied Research Leveraging the ISS National Lab

The purpose of this NLRA is to solicit proposals focused on flight investigations within applied R&D, translational medicine, technology readiness level maturation, and technology demonstrations.

Past Opportunity  
casis academy live1280

Open Period: 3/18/2022 – 7/19/2022

NLRA 2022-7: Leveraging the ISS National Lab to Enable Digital Engagement For K-12 and...

The purpose of this NLRA is to solicit applications for programs, products, and public-private partnerships focused on educational objectives related to the ISS National Lab.

Past Opportunity  
Aeropyrum pernix Flap Endonuclease 1 (FEN 1) protein crystals are shown grown under Earth gravity conditions. FEN 1 serves as the experimental protein for the Phase II Real time Protein Crystal Growth on Board the International Space Station (Real Time Protein Crystal Growth 2) investigation.

Open Period: 2/14/2022 – 6/15/2022

NLRA 2022-6: In-space Production Applications: Advanced Materials and Manufacturing

The purpose of this ISS National Lab Research Announcement is to solicit proposals for applied R&D to demonstrate space-based manufacturing and production activities in microgravity.

Past Opportunity  
View of a bubble formed as a result of a Zeolite Crystal Growth (ZCG) experiment in the Destiny laboratory on the International Space Station

Open Period: 12/23/2021-3/21/2022

NSF/CASIS 2022 Collaboration on Transport Phenomena Research on the ISS to Benefit Life on...

The purpose of this solicitation is to attract proposals to leverage ISS National Lab for research related to the NSF Transport Phenomena Cluster and Nanoscale Interaction programs.

Past Opportunity  
NASA astronaut Christina Koch sets up Fiber Optic Production, an investigation to create optical fibers in microgravity that may exhibit superior quality to those produced on Earth.

Open Period: Cycle 1: 12/7/2021-5/2/202 Cycle 2: 3/15/2022-10/17/2022

NLRA 2022-5: Technology Advancement and Applied Research Leveraging the ISS National Lab

The purpose of this NLRA is to solicit proposals for flight investigations within applied R&D, translational medicine, technology readiness level maturation, and tech demo.

Past Opportunity  
A close up view of the cell culture media change in a chamber containing engineered heart tissues as part of the Cardinal Heart experiment aboard the International Space Station

Open Period: 12/3/2021-3/8/2022

NSF/CASIS 2022 Collaboration on Tissue Engineering and Mechanobiology on the ISS to Benefit...

The purpose of this solicitation is to attract proposals that make use of the ISS National Lab for flight research projects in the field of biomedical engineering.

Past Opportunity  
ISS National Lab Sustainability Challenge logo

Open Period: 10/28/2021 – 5/9/2022

ISS National Lab Sustainability Challenge: Beyond Plastics

The ISS National Lab Sustainability Challenge: Beyond Plastics aims to utilize the orbiting laboratory to advance sustainability research that addresses the plastics dilemma.

Past Opportunity  
organ bioengineering microgravity cover image

Open Period: 3/22/2021 – 7/12/2021

NLRA 2021-6: In-space Production Applications: Tissue Engineering and Biomanufacturing

The purpose of this ISS National Lab Research Announcement (NLRA) is to solicit proposals for applied R&D to demonstrate space-based biomanufacturing activities in microgravity.

Past Opportunity  
NASA astronaut Jessica Meir onboard the ISS working with engineered heart tissues. This investigation is examining the effects of microgravity on human cardiac tissue structure and physiological function.

Open Period: 10/19/2021 – 3/21/2022

NLRA 2022-3: In-Space Production Applications: Tissue Engineering and Biomanufacturing

The purpose of this NLRA is to solicit proposals for applied research and development seeking to demonstrate space-based biomanufacturing activities in microgravity.

Past Opportunity